Adiponectin, fat distribution and insulin resistance

Adiponectin, a peptide hormone that is secreted from fat cells, appears to be part of the fat distribution puzzle. Subjects with higher adiponectin had less insulin resistance and lower waist circumferences. Moderate weight loss did not change adiponectin levels…so the fat distribution signal was still in place.

Injections of adiponectin have had positive results in mice. Fish oil and some diabetes drugs raise adiponectin.


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